It starts in the area of Frosinone from the confluence between the Liri, which first crosses Abruzzo and Lazio, and the Gari, which rises at Cassino and is often called Liri-Garigliano.
Although its name derives from the Oscan word tifata, which means holm oak, Mount Tifata is largely barren, except for the woods surrounding the northern side.
For the ancients, it was the river of the myth, which gave forgetfulness to whoever drunk its water.
The longest river of Southern Italy with its 175 kilometres rises in Molise, at Rocchetta a Volturno and runs for a long way in the Apennine region, of which, after the Ponte 25 archi, marks the border with Campania.